How could relapse in leukemia after CAR T treatment—a problem that still affects between 30–60% of patients—be prevented? One major driver is antigen escape: leukemia […]
Resident Macrophages Play a Role in Maintaining Murine Intraocular Pressure
When the eye’s drainage system clogs, intraocular pressure (IOP) builds up and causes damage. The pressure can lead to glaucoma and vision loss. Researchers headed […]
Polyphenol mediated zinc-oxygen synergistic hydrogel remodels senescent microenvironment for periodontal tissue regeneration
References Hajishengallis, G. Periodontitis: from microbial immune subversion to systemic inflammation. Nat. Rev. Immunol. 15, 30–44 (2015). Google Scholar Aquino-Martinez, R. The emerging role of […]
Synergistic immunotherapeutic effects of irreversible electroporation and CAR-NK cell therapy against hepatocellular carcinoma
Introduction Liver cancer is one of the leading causes of cancer-related deaths.1 Hepatocellular carcinoma (HCC), the predominant type of primary liver cancer, presents a serious […]
Gene edit makes probiotic safer for immunocompromised patients
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How AI could unlock deep‑sea secrets of marine life
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CRISPR-based technique unlocks healing power of mitochondria for heart failure therapy
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In Vivo CAR T Therapy Will the Bets Pay Off?
The value of ex vivo autologous CAR T therapies is clear: for some patients, these treatments offer a second chance at life. Yet the approach […]
Top 10 Takeover Targets of 2026
The year has gotten off to a warm start, though not quite red hot, when it comes to biopharma merger-and-acquisition (M&A) deals. Market watchers rang […]
Expanding the Druggable Proteome with Tech Advances
Drug discovery has long faced a stubborn reality: Most disease-relevant proteins lack the deep, hydrophobic pockets required for inhibition by conventional small-molecule drugs. Beginning in […]
