Jacob Berlin, PhD, CEO of Terray Therapeutics, explains that the critical element to “get right” for a preclinical drug discovery campaign is identifying molecules that […]
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Microbial biomining from asteroidal material onboard the international space station
ReferencesVerseux, C. et al. Sustainable life support on Mars - The potential roles of cyanobacteria. Int. J. Astrobiol. 15, 65–92 (2016). Google Scholar Gumulya, Y., Zea, L. & Kaksonen, A. H. In situ resource utilisation:…
Microbial consortia for the conversion of biomass into fuels and chemicals
IntroductionAs part of the multiform effort to obviate fossil-based resource consumption, biomass represents a viable…
Robots on the Red Line: A Video Update from SLAS 2026
Automation—and the SLAS meeting dedicated to it—continues to grow bigger and more exciting each year. Reporting from the meeting in Boston, Julianna LeMieux, PhD, and […]
Exploring the mammalian metabolome with DeepMet
Mammalian metabolic maps based on mass spectrometry are largely incomplete. Addressing the challenges in the dark matter of the metabolome requires technical and computational innovations. […]
Biohybrid robots evolutionized by soft electronics
Introduction Bio-hybrid robots are a class of soft robots that incorporate living muscle tissues as biological actuators integrated with synthetic scaffolds, enabling biomimetic motion through […]
Cranberry extract-supplemented microbiota effluents enhance intestinal barrier integrity via mucin production and antimicrobial activity in murine organoids
References Neilson, A. P., O’Keefe, S. F. & Bolling, B. W. High-Molecular-Weight proanthocyanidins in foods: overcoming analytical challenges in pursuit of novel dietary bioactive components. […]
Phage-antibiotic synergistic effect for treating cutaneous wounds infections caused by MRSA and the assessment of wound healing biomarkers in a rabbit model
References El-Far, A. et al. Assessment of eugenol inhibitory effect on biofilm formation and biofilm gene expression in methicillin resistant Staphylococcus aureus clinical isolates in […]
De novo generation and in silico screening of anti-diabetic peptide candidates via a deep learning–attention framework with physicochemical feature fusion
References Hajfathalian, M., Ghelichi, S. & Jacobsen, C. Anti-obesity peptides from food: Production, evaluation, sources, and commercialization. Compr. Rev. Food Sci. Food Saf. 24 (2), […]
PRICE: direct and robust detection of microRNAs at single-nucleotide resolution
Data availability The main data supporting the findings of this study are available within the paper and its Supplementary Information. All the original data generated […]
Silk fibroin-coated resveratrol solid lipid nanoparticles for diabetic wound healing
References Deng, P. et al. Worldwide research trends on diabetic foot ulcers (2004–2020): Suggestions for researchers. J. Diabetes Res. 2022, 7592321. https://doi.org/10.1155/2022/7592321 (2022). Google Scholar […]
dHyperCas12a enables multiplexed CRISPRi screens
References Joo, J.-Y., Schaukowitch, K., Farbiak, L., Kilaru, G. & Kim, T.-K. Stimulus-specific combinatorial functionality of neuronal c-fos enhancers. Nat. Neurosci. 19, 75–83 (2016). Google […]