Novasign and Repligen entered into a strategic partnership to develop and integrate Novasign’s machine learning and modeling workflow into Repligen filtration systems. As part of the partnership, Repligen will invest in Novasign to help scale and expand operations.
Through this collaboration, Novasign’s modeling workflow will be integrated into Repligen’s tangential flow filtration (TFF) systems, according to a Repligen spokesperson, who adds that this will not only enhance Repligen’s digitalization journey and strengthen its portfolio of process analytical technology (PAT)-enabled systems but will also unlock the potential for future advanced AI modeling within Repligen platforms. The end goal is to streamline process development, enable real-time predictive control, and significantly reduce development timelines and costs through the deployment of digital twins.
Novasign brings together expertise in bioprocessing, modeling, and software engineering to deliver AI-powered solutions across cultivation, harvest, filtration, and chromatography, explains Mark Duerkop, CEO. The company’s multi-use models extract actionable insights from experimental data and can be readily applied to new modalities, products, and scales, he continues, noting that the net result is smarter process development, enhanced monitoring and control, and a significant reduction in time, cost, and risk.
“By integrating our automated manufacturing systems with smart sensors and Novasign’s digital twins capability, we will provide technology to accelerate process development and ensure a more efficient and reliable scale-up for our customers,” say Ralf Kurivel, senior vice president, R&D at Repligen.
“The fusion of intelligent modeling workflows, PAT and smart devices will allow the industry to drastically reduce development costs while unlocking deeper process understanding,” maintains Duerkop. “We’ve already laid the groundwork for this collaboration through earlier joint efforts with Repligen on its PAT technologies, and we’re proud to now take it to the next level with joint development. This strategic partnership represents a strong endorsement of Novasign’s innovation and long-term role in advancing bioprocess digitalization.”
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