Implantable neural probes with monolithically integrated CNTFET arrays for multimodal monitoring

implantable-neural-probes-with-monolithically-integrated-cntfet-arrays-for-multimodal-monitoring
Implantable neural probes with monolithically integrated CNTFET arrays for multimodal monitoring

Data availability

All data supporting the findings of this study are available within the article and its supplementary files. Any additional requests for information can be directed to, and will be fulfilled by, the corresponding authors. Source data are provided with this paper.

Code availability

The custom code used in this study is available on Zenodo under the https://doi.org/10.5281/zenodo.17547948 (2025)55.

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Acknowledgements

Shurong Dong, Gang Pan, Jikui Luo, Shaomin Zhang et al. would like to thank STI2030-Major Projects (No. 2021ZD0200401). Shurong Dong would like to thank Zhejiang Province high level talent special support plan (No. 2022R52042), Zhejiang Province Key R & D programs (No. 2024C03001, No. 2024C03007). Zhen Cao would like to thank Zhejiang Province Leading Geese Plan (No. 2024C03217). Yanlan Yu would like to thank Medical Interdisciplinary Innovation Program 2024, Zhejiang University School of Medicine. The authors would like to express their gratitude to Prof. Tawfique Hasan (Department of Engineering, University of Cambridge, UK) for the collaboration and technical consultations. We also thank Jingyao Chen, Qiong Huang, Chengcheng Zhang, and Yajun Yu from the core facility platform of Zhejiang University School of Medicine for their technical support, and Xu Bin from Zhejiang University 7 T Brain Imaging Research Center for assistance. We further acknowledge Hangzhou Rong brain Technology Co., Ltd. for assisting with the LFP collection, and process engineers from Haijiexing Technology Co., Ltd. (Suzhou, China) for sharing their expertise inlaser internal modification and providing relevant equipment.

Author information

Authors and Affiliations

  1. The State Key Lab of Brain-Machine Intelligence, Zhejiang University, Hangzhou, China

    Jie Xia, Luxi Zhang, Shengming Wang, Fan Zhang, Shaomin Zhang, Jikui Luo, Gang Pan, Zhen Cao & Shurong Dong

  2. Department of Urology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China

    Yanlan Yu, Guoqing Ding & Shurong Dong

  3. Key Laboratory for the Physics and Chemistry of Nanodevices and Center for Carbon-based Electronics, School of Electronics, Peking University, Beijing, China

    Li Ding

  4. Department of Engineering, University of Cambridge, Cambridge, UK

    Yan Yan Shery Huang & Luigi Occhipinti

  5. Zhejiang Provincial Engineering Research Center of Innovative Instruments for Precise Pathogen Detection, Hangzhou, China

    Zhen Cao

Authors

  1. Jie Xia
  2. Luxi Zhang
  3. Shengming Wang
  4. Yanlan Yu
  5. Li Ding
  6. Fan Zhang
  7. Shaomin Zhang
  8. Jikui Luo
  9. Yan Yan Shery Huang
  10. Luigi Occhipinti
  11. Gang Pan
  12. Zhen Cao
  13. Guoqing Ding
  14. Shurong Dong

Contributions

J.X. and S.D. developed the methodology, acquired the data, and wrote the manuscript. L.Z., Y.Y. and F.Z. conducted the animal experiments. S.W. and L.D. performed data analysis. S.Z., L.D. and G.D. contributed to methodology development and manuscript revision. S.D. supervised the project. G.P. and S.D. provided funding and supervised the study. Z.C. contributed to manuscript revision and supervision. J.L., Y.Y.S.H. and L.O. contributed to manuscript revision.

Corresponding authors

Correspondence to Gang Pan, Zhen Cao, Guoqing Ding or Shurong Dong.

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The authors declare no competing interests.

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Nature Communications thanks Mariana Branco and the other anonymous reviewer(s) for their contribution to the peer review of this work. A peer review file is available.

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Xia, J., Zhang, L., Wang, S. et al. Implantable neural probes with monolithically integrated CNTFET arrays for multimodal monitoring. Nat Commun (2025). https://doi.org/10.1038/s41467-025-67535-5

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  • DOI: https://doi.org/10.1038/s41467-025-67535-5