Impact of dietary replacement of soybean meal with high-protein wheat on gut microbial metabolism in chickens

impact-of-dietary-replacement-of-soybean-meal-with-high-protein-wheat-on-gut-microbial-metabolism-in-chickens
Impact of dietary replacement of soybean meal with high-protein wheat on gut microbial metabolism in chickens

References

  1. Elling-Staats, M. L., Gilbert, M. S., Smidt, H. & Kwakkel, R. P. Caecal protein fermentation in broilers: a review. Worlds Poult. Sci. J. 78, 103–123. https://doi.org/10.1080/00439339.2022.2003170 (2022).

    Google Scholar 

  2. Selle, P. H., Macelline, S. P., Greenhalgh, S., Chrystal, P. V. & Liu, S. Y. Identifying the shortfalls of crude protein-reduced, wheat-based broiler diets. Anim. Nutr. 11, 181–189. https://doi.org/10.1016/j.aninu.2022.07.009 (2022).

    Google Scholar 

  3. Szuba-Trznadel, A. et al. Diversity of chemical composition and nutritional value in grain from selected winter wheat cultivars grown in south-western Poland. Sci. Rep. 14, 2630. https://doi.org/10.1038/s41598-024-53094-0 (2024).

    Google Scholar 

  4. Ding, X., Giannenas, I., Skoufos, I., Wang, J. & Zhu, W. The effects of plant extracts on lipid metabolism of chickens – A review. Anim. Biosci. 36, 679–691. https://doi.org/10.5713/ab.22.0272 (2023).

    Google Scholar 

  5. Sugiharto, S. Role of nutraceuticals in gut health and growth performance of poultry. J. Saudi Soc. Agric. Sci. 15, 99–111. https://doi.org/10.1016/j.jssas.2014.06.001 (2016).

    Google Scholar 

  6. Ali, Q. et al. Microbial short-chain fatty acids: a bridge between dietary fibers and poultry gut health — A review. Anim. Biosci. 35, 1461–1478. https://doi.org/10.5713/ab.21.0562 (2022).

    Google Scholar 

  7. Sun, Y. & O’Riordan, M. X. D. Regulation of bacterial pathogenesis by intestinal short-chain fatty acids. Adv. Appl. Microbiol. 85, 93–118. https://doi.org/10.1016/B978-0-12-407672-3.00003-4 (2013).

    Google Scholar 

  8. Sakata, T. Effect of short-chain fatty acids on the proliferation of gut epithelial cells in vivo. In Physiological and clinical aspects of short-chain fatty acids (eds Cummings, J. H. et al.) 289–305 (Cambridge University Press, 1995).

    Google Scholar 

  9. Nilsson, N. E., Kotarsky, K., Owman, C. & Olde, B. Identification of a free fatty acid receptor, FFA2, expressed on leukocytes and activated by short-chain fatty acids. Biochem. Biophys. Res. Commun. 301, 406–410 (2003).

    Google Scholar 

  10. Ross Broiler Management Handbook. Provision of feed and water. (2018). https://aviagen.com/assets/Tech_Center/Ross_Broiler/Ross-BroilerHandbook2018-EN.pdf

  11. Szuba-Trznadel, A. et al. Evaluating high-protein wheat as a protein source for broiler chicken. Sci. Rep. 15, 31896. https://doi.org/10.1038/s41598-025-17803-7 (2025).

    Google Scholar 

  12. Broiler Nutrition Specifications. (2019). https://aviagen.com/eu/brands/ross/products/ross-308

  13. Smulikowska, S. & Rutkowski, A. (eds),. The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Jabłonna, and World’s Poultry Science Association (Poznań, Poland (2018).

  14. McDougall, E. I. Studies on ruminant saliva. 1. The composition and output of sheep’s saliva. Biochem. J. 43, 99–109. https://doi.org/10.1042/bj0430099 (1948).

    Google Scholar 

  15. Miśta, D. et al. Effect of in ovo injected prebiotics and synbiotics on the caecal fermentation and intestinal morphology of broiler chickens. Anim. Prod. Sci. 57, 1884–1892. https://doi.org/10.1071/AN16257 (2017).

    Google Scholar 

  16. Ørskov, E. R. Manipulation of rumen fermentation for maximum food utilization. World Rev. Nutr. Diet. 22, 153–182 (1975).

    Google Scholar 

  17. Abrahamse, P. A., Vlaeminck, B., Tamminga, S. & Dijkstra, J. The effect of silage and concentrate type on intake behavior, rumen function, and milk production in dairy cows in early and late lactation. J. Dairy. Sci. 91, 4778–4792. https://doi.org/10.3168/jds.2008-1350 (2008).

    Google Scholar 

  18. Core Team, R. R. A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. (2021). https://www.R-project.org

  19. Wickham, H. ggplot2: Elegant graphics for data analysis (Springer-, 2016). https://ggplot2.tidyverse.org

  20. Payvastegan, S., Farhoomand, P., Daneshyar, M. & Ghaffari, M. Evaluation of different levels of canola meal on performance, organ weights, hepatic deiodinase gene expression and thyroid morphology in broiler chickens. J. Poult. Sci. 54, 282–291. https://doi.org/10.2141/jpsa.0160147 (2017).

    Google Scholar 

  21. Rama Rao, S. V., Raju, M. V., Panda, A. K. & Reddy, M. R. Sunflower seed meal as a substitute for soybean meal in commercial broiler chicken diets. Br. Poult. Sci. 47, 592–598. https://doi.org/10.1080/00071660600963511 (2006).

    Google Scholar 

  22. Murawska, D. et al. Partial and total replacement of soybean meal with full-fat black soldier fly (Hermetia illucens L.) larvae meal in broiler chicken diets: impact on growth performance, carcass quality and meat quality. Animals 11, 2715. https://doi.org/10.3390/ani11092715 (2021).

    Google Scholar 

  23. Marchal, L., Bello, A., Archer, G., Sobotik, E. B. & Dersjant-Li, Y. Total replacement of soybean meal with alternative plant-based ingredients and a combination of feed additives in broiler diets from 1 day of age during the whole growing period. Poult. Sci. 103, 103854. https://doi.org/10.1016/j.psj.2024.103854 (2024).

    Google Scholar 

  24. Jørgensen, H., Zhao, X. Q., Knudsen, K. E. & Eggum, B. O. The influence of dietary fibre source and level on the development of the gastrointestinal tract, digestibility and energy metabolism in broiler chickens. Br. J. Nutr. 75, 379–395. https://doi.org/10.1079/bjn19960141 (1996).

    Google Scholar 

  25. Sanchez, J., Barbut, S., Patterson, R. & Kiarie Impact of fiber on growth, plasma, gastrointestinal and excreta attributes in broiler chickens and turkey poults fed corn- or wheat-based diets with or without multienzyme supplement. Poult. Sci. 100, 101219. https://doi.org/10.1016/j.psj.2021.101219 (2021).

    Google Scholar 

  26. Baker, J. T., Duarte, M. E., Holanda, D. M. & Kim, S. W. Friend or Foe? Impacts of Dietary Xylans, Xylooligosaccharides, and Xylanases on Intestinal Health and Growth Performance of Monogastric Animals. Animals 11, 609. https://doi.org/10.3390/ani11030609 (2021).

    Google Scholar 

  27. Stevens, E. & Hume, I. D. Contributions of microbes in vertebrate gastrointestinal tract to production and conservation of nutrients. Physiol. Rev. 78, 393–427 (1998).

    Google Scholar 

  28. Hunt, A., Al-Nakkash, L., Lee, A. H. & Smith, H. F. Phylogeny and herbivory are related to avian cecal size. Sci. Rep. 9, 4243. https://doi.org/10.1038/s41598-019-40822-0 (2019).

    Google Scholar 

  29. Morgan, N. K. Advances in prebiotics for poultry: role of the caeca and oligosaccharides. Anim. Prod. Sci. 63, 1911–1925. https://doi.org/10.1071/AN23011 (2023).

    Google Scholar 

  30. Poppema, T. F. Relationships of cecal lengths to food habits in North American and other birds. MS thesis, Florida Atlantic University, Boca Raton, FL, USA (1990).

  31. Svihus, B., Choct, M. & Classen, H. L. Function and nutritional roles of the avian caeca: a review. World’s Poult. Sci. J. 69, 249–263. https://doi.org/10.1017/S0043933913000287 (2013).

    Google Scholar 

  32. Józefiak, D., Rutkowski, A. & Martin, S. A. Carbohydrate fermentation in the avian ceca: a review. Anim. Feed Sci. Technol. 113, 1–15. https://doi.org/10.1016/j.anifeedsci.2003.09.007 (2004).

    Google Scholar 

  33. Metzler-Zebeli, B. U. et al. Differences in intestinal size, structure, and function contributing to feed efficiency in broiler chickens reared at geographically distant locations. Poult. Sci. 97, 578–591. https://doi.org/10.3382/ps/pex332 (2018).

    Google Scholar 

  34. Shang, Y., Kumar, S. & Oakley, B. Kim & W.K. Chicken gut microbiota: importance and detection technology. Front. Vet. Sci. 5, 254. https://doi.org/10.3389/fvets.2018.00254 (2018).

    Google Scholar 

  35. Han, G. G. et al. Relationship between the microbiota in different sections of the gastrointestinal tract, and the body weight of broiler chickens. SpringerPlus 5, 911. (2016). https://doi.org/10.1186/s40064-016-2604-8

  36. Kumar, S. et al. Effect of antibiotic withdrawal in feed on chicken gut microbial dynamics, immunity, growth performance and prevalence of foodborne pathogens. PLoS One. 13, e0192450. https://doi.org/10.1371/journal.pone.0192450 (2018).

    Google Scholar 

  37. Wei, S., Morrison, M. & Yu, Z. Bacterial census of poultry intestinal microbiome. Poult. Sci. 92, 671–683. https://doi.org/10.3382/ps.2012-02822 (2013).

    Google Scholar 

  38. Rychlik, I. Composition and function of chicken gut microbiota. Animals 10, 103. https://doi.org/10.3390/ani10010103 (2020).

    Google Scholar 

  39. Aruwa, C. E., Pillay, C., Nyaga, M. M. & Sabiu, S. Poultry gut health – microbiome functions, environmental impacts, microbiome engineering and advancements in characterization technologies. J. Anim. Sci. Biotechnol. 12, 119. https://doi.org/10.1186/s40104-021-00640-9 (2021).

    Google Scholar 

  40. Sergeant, M. J. et al. Extensive microbial and functional diversity within the chicken cecal microbiome. PLoS One 9, e91941. https://doi.org/10.1371/journal.pone.0091941.

  41. Liu, Y. S. et al. Microbiota populations and short-chain fatty acids production in cecum of immunosuppressed broilers consuming diets containing γ-irradiated Astragalus polysaccharides. Poult. Sci. 100, 273–282. https://doi.org/10.1016/j.psj.2020.09.089 (2021).

    Google Scholar 

  42. Panth, Y. Colibacillosis in poultry: a review. J. Agric. Nat. Res. 2, 301–311. https://doi.org/10.3126/janr.v2i1.26094 (2019).

    Google Scholar 

  43. Gonzalez-Ortiz, G., Olukosi, O. A., Jurgens, M., Apajalahti, J. & Bedford, M. R. Short-chain fatty acids and ceca microbiota profiles in broilers and turkeys in response to diets supplemented with phytase at varying concentrations, with or without xylanase. Poult. Sci. 99, 2068–2077. https://doi.org/10.1016/j.psj.2019.11.051 (2020).

    Google Scholar 

  44. Yin, Z. et al. Cecal microbial succession and its apparent association with nutrient metabolism in broiler chickens. mSphere 8, e0061422. https://doi.org/10.1128/msphere.00614-22 (2023).

    Google Scholar 

  45. Zhu, X., Tao, L., Liu, H. & Yang, G. Effects of fermented feed on growth performance, immune organ indices, serum biochemical parameters, cecal odorous compound production, and the microbiota community in broilers. Poult. Sci. 102, 102629. https://doi.org/10.1016/j.psj.2023.102629 (2023).

    Google Scholar 

  46. Rybicka, A., del Pozo, R., Carro, D. & Garcia, J. Effect of type of fiber and its physicochemical properties on performance, digestive transit time, and cecal fermentation in broilers from 1 to 23 d of age. Poult. Sci. 103, 103192. https://doi.org/10.1016/j.psj.2023.103192 (2024).

    Google Scholar 

  47. Bergman, E. N. Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. Physiol. Rev. 70, 567–590 (1990). PMID: 2181501.

    Google Scholar 

  48. Liu, X. et al. Age-associated changes in the growth development of abdominal fat and their correlations with cecal gut microbiota in broiler chickens. Poult. Sci. 102, 102900. https://doi.org/10.1016/j.psj.2023.102900 (2023).

    Google Scholar 

  49. Carvalho, N. M., Oliveira, D. L., Saleh, M. A. D., Pintado, M. E. & Madureira, A. R. Importance of gastrointestinal in vitro models for the poultry industry and feed formulations. Anim. Feed Sci. Technol. 271, 114730. https://doi.org/10.1016/j.anifeedsci.2020.114730 (2021).

    Google Scholar 

  50. Brestenský, M. et al. The content of short chain fatty acids in the jejunal digesta, caecal digesta and faeces of growing pigs. Livest. Sci. 205, 106–110. https://doi.org/10.1016/j.livsci.2017.09.015 (2017).

    Google Scholar 

  51. McCafferty, K. W., Bedford, M. R., Kerr, B. J. & Dozier, W. A. Effects of age and supplemental xylanase in corn- and wheat-based diets on cecal volatile fatty acid concentrations of broilers. Poult. Sci. 98, 4787–4800. https://doi.org/10.3382/ps/pez194 (2019).

    Google Scholar 

  52. Liao, X. et al. The relationship among gut microbiota, short-chain fatty acids, and intestinal morphology of growing and healthy broilers. Poult. Sci. 99, 5883–5895. https://doi.org/10.1016/j.psj.2020.08.033 (2020).

    Google Scholar 

  53. Szendrő, Z. Poultry farming does not play a significant role in global warming – a review. Ann. Anim. Sci. 24, 631–643 (2024).

    Google Scholar 

  54. Marounek, M. & Rada, V. Effect on in vitro fermentation pattern and methane production in the caeca of chickens. Physiol. Res. 47, 259–263 (1998).

    Google Scholar 

  55. Saengkerdsub, S., Kim, W. K., Anderson, R. C., Nisbet, D. J. & Ricke, S. C. Effects of nitro compounds and feedstuffs on in vitro methane production in chicken cecal contents and rumen fluid. Anaerobe 12, 85–92 (2006).

    Google Scholar 

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