Bioactive-fat engineered nanostructured lipid carriers from Illipe butter: optimized design and enhanced in vitro anti-inflammatory performance

Posted on
bioactive-fat-engineered-nanostructured-lipid-carriers-from-illipe-butter:-optimized-design-and-enhanced-in-vitro-anti-inflammatory-performance
Bioactive-fat engineered nanostructured lipid carriers from Illipe butter: optimized design and enhanced in vitro anti-inflammatory performance

References

  1. Sahle, F. F., Gebre-Mariam, T., Dobner, B., Wohlrab, J. & Neubert, R. H. H. Skin diseases associated with depletion of stratum corneum lipids and lipid substitution therapy. Skin Pharmacol. Physiol. 28(1), 42–55. https://doi.org/10.1159/000360009 (2014).

    Google Scholar 

  2. Lin, T. K., Zhong, L. & Santiago, J. L. Anti-inflammatory and skin barrier repair effects of topical application of some plant oils. Int. J. Mol. Sci. 19(1), 70. https://doi.org/10.3390/ijms19010070 (2017).

    Google Scholar 

  3. Krist, S., 2020. Illipe Butter BT – Vegetable Fats and Oils, in: Krist, S. (Ed.), . Springer International Publishing, Cham, pp. 361–367. https://doi.org/10.1007/978-3-030-30314-3

  4. Puspita, D., Wulandari, T. S. & Wahyu, F. D. Analysis of bioactive compounds in Sengkawang oil (Shorea sumatrana) by GC–MS. Journal of Food Technology and Nutrition 18(2), 64–73 (2019).

    Google Scholar 

  5. Warnida, H., Sukawaty, Y. & Ardhita, F. W. Comparison of lipstick formulations based on illipe butter (tengkawang) and cocoa butter. Manuntung Scientific Journal 6(2), 103–109 (2020).

    Google Scholar 

  6. Gunstone, F. D. (2020). Vegetable Oils in Food Technology: Composition, Properties and Uses. Wiley-Blackwell.

  7. Aini, N., Hariyadi, P. & Purnomo, E. H. Physical and chemical properties of Illipe butter (Shorea spp.) and its potential as cocoa butter substitute. Int. Food Res. J. 26(1), 207–214 (2019).

    Google Scholar 

  8. Müller, R. H., Radtke, M. & Wissing, S. A. Nanostructured lipid matrices for improved microencapsulation of active compounds. Int. J. Pharm. 242(1–2), 121–128 (2011).

    Google Scholar 

  9. Souto, E. B. et al. SLN and NLC for topical, dermal, and transdermal drug delivery. Expert Opin. Drug Deliv. 17(3), 357–377. https://doi.org/10.1080/17425247.2020.1727883 (2020).

    Google Scholar 

  10. Apostolou, M., Assi, S., Fatokun, A. A. & Khan, I. The effects of solid and liquid lipids on the physicochemical properties of nanostructured lipid carriers. J. Pharm. Sci. 110, 2859–2872. https://doi.org/10.1016/j.xphs.2021.04.012 (2021).

    Google Scholar 

  11. Naseri, N., Valizadeh, H. & Zakeri-Milani, P. Solid lipid nanoparticles and nanostructured lipid carriers: Structure, preparation, and application. Adv. Pharm. Bull. 5(3), 305–313 (2015).

    Google Scholar 

  12. Patel, M. H., Patel, J. K. & Patel, R. P. Role of lipid and surfactant composition on NLC characteristics. J. Drug Deliv. Sci. Technol. 57, 101640 (2020).

    Google Scholar 

  13. Ferreira, S. L. C. et al. Box–Behnken design: An alternative for the optimization of analytical methods. Anal. Chim. Acta 597(2), 179–186 (2007).

    Google Scholar 

  14. Beg, S., Akhter, S., 2021. Box–Behnken Designs and Their Applications in Pharmaceutical Product Development BT – Design of Experiments for Pharmaceutical Product Development: Volume I : Basics and Fundamental Principles, in: Beg, S. (Ed.),. Springer Singapore, Singapore, 77–85. https://doi.org/10.1007/978-981-33-4717-5_7

  15. Sohail, M., Rehman, A., Hussain, S. & Ahmed, S. Anti-inflammatory properties of fatty acids and their derivatives. J. Inflamm. Res. 13, 627–642 (2020).

    Google Scholar 

  16. Tamjidi, F., Shahedi, M., Varshosaz, J. & Nasirpour, A. Nanostructured lipid carriers (NLC): A potential delivery system for bioactive food molecules. Innov. Food Sci. Emerg. Technol. 19, 29–43 (2013).

    Google Scholar 

  17. Ferreira, S. L. C. et al. Box–Behnken design: An alternative for the optimization of analytical methods. Anal. Chim. Acta 597(2), 179–186 (2007).

    Google Scholar 

  18. O’Fallon, J. V., Busboom, J. R., Nelson, M. L. & Gaskins, C. T. A direct method for fatty acid methyl ester synthesis. J. Anim. Sci. 85, 1511–1521 (2007).

    Google Scholar 

  19. Mizushima, Y. & Kobayashi, M. Interaction of anti-inflammatory drugs with serum proteins. J. Pharm. Pharmacol. 20(3), 169–173 (1968).

    Google Scholar 

  20. Williams, L. A. D. et al. The in vitro anti-denaturation effects induced by natural products and non-steroidal compounds in heat-treated bovine serum albumin. West Indian Med. J. 57(4), 327–331 (2008).

    Google Scholar 

  21. Salvi, V. R. & Pawar, P. Nanostructured lipid carriers (NLC) system: A novel drug targeting carrier. J. Drug Deliv. Sci. Technol. 51, 255–267 (2019).

    Google Scholar 

  22. Azhar Shekoufeh Bahari, L. & Hamishehkar, H. The impact of variables on particle size of solid lipid nanoparticles and nanostructured lipid carriers; a comparative literature review. Adv. Pharm. Bull. 6(2), 143–151 (2016).

    Google Scholar 

  23. Danaei, M. et al. Impact of particle size and polydispersity index on the clinical applications of lipidic nanocarrier systems. Pharmaceutics 10, 57 (2018).

    Google Scholar 

  24. Bahari, L. A. S. & Hamishehkar, H. The impact of variables on particle size of solid lipid nanoparticles and nanostructured lipid carriers; a comparative literature review. Adv. Pharm. Bull. 6, 143 (2016).

    Google Scholar 

  25. Akhoond Zardini, A., Mohebbi, M., Farhoosh, R. & Bolurian, S. Production and characterization of nanostructured lipid carriers and solid lipid nanoparticles containing lycopene for food fortification. J. Food Sci. Technol. 55, 287–298 (2018).

    Google Scholar 

  26. Khalil, R.M., Abd El-Bary, A., Kassem, M.A., Ghorab, M.M., Ahmed, M.B., 2013. Solid lipid nanoparticles for topical delivery of meloxicam: development and in vitro characterization. Eur. Sci. J. 9.

  27. Hu, F.-Q. et al. Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system. Colloids Surf., B 45, 167–173 (2005).

    Google Scholar 

  28. Chen, J. et al. Glucosaminederivative modified nanostructured lipid carriers for targeted tumor delivery. J. Mater. Chem. 22, 5770–5783 (2012).

    Google Scholar 

  29. Nazarova, O. et al. Surface charge modification and porosity control of lipid nanocarriers via surfactant ratio. Colloids Surf A Physicochem Eng Aspects 643, 128749 (2022).

    Google Scholar 

  30. Hiemenz, P. C. & Rajagopalan, R. Principles of Colloid and Surface Chemistry, revised and expanded (CRC Press, 2016).

    Google Scholar 

  31. Emami, J. et al. Influence of formulation variables on the zeta potential and stability of lipid-based nanocarriers. Colloids Surf B Biointerfaces 95, 11–18 (2012).

    Google Scholar 

  32. Shnoudeh, A.J., Hamad, I., Abdo, R.W., Qadumii, L., Jaber, A.Y., Surchi, H.S., Alkelany,S.Z., 2019. Chapter 15 – Synthesis, Characterization, and Applications of Metal Nanoparticles, in: Tekade, R.K.B.T.-B. and B. (Ed.), Advances in Pharmaceutical Product Development and Research. Academic Press, pp. 527–612.

  33. Chen, Y., Zhang, H., Wang, Y. & Yang, Y. Influence of surfactant ratio on zeta potential and particle size of lipid nanoparticles. Int J Nanomedicine 7, 1841–1850 (2012).

    Google Scholar 

  34. Khan, S., Sharma, A. & Jain, V. An overview of nanostructured lipid carriers and its application in drug delivery through different routes. Adv. Pharm. Bull. 13(3), 446–460 (2023).

    Google Scholar 

  35. Eh Suk, V. R., Mohd Latif, F., Teo, Y. Y. & Misran, M. Development of nanostructured lipid carrier (NLC) assisted with polysorbate nonionic surfactants as a carrier for l-ascorbic acid and Gold Tri.E 30. J. Food Sci. Technol. 57, 3259–3266. https://doi.org/10.1007/s13197-020-04357-x (2020).

    Google Scholar 

  36. Lukić, M., Pantelić, I. & Savić, S. D. Towards optimal pH of the skin and topical formulations: From the current state of the art to tailored products. Cosmetics 8(3), 69. https://doi.org/10.3390/cosmetics8030069 (2021).

    Google Scholar 

  37. Yılmaz Usta, D., Teksin, Z. S. & Tugcu-Demiroz, F. Evaluation of emulgel and nanostructured lipid carrier-based gel formulations for transdermal administration of ibuprofen. AAPS PharmSciTech 25(2), 124 (2024).

    Google Scholar 

  38. Budai, L., Budai, M., Fülöpné Pápay, Z. E., Vilimi, Z. & Antal, I. Rheological considerations of pharmaceutical formulations: Focus on viscoelasticity. Gels https://doi.org/10.3390/gels9060469 (2023).

    Google Scholar 

  39. Salsinha, A. S., Socodato, R., Relvas, J. B., & Pintado, M. (2023). The pro- and anti-inflammatory activity of fatty acids. In M. Pintado et al. (Eds.), Bioactive Lipids (pp. 51–75). Academic Press. https://doi.org/10.1016/B978-0-12-824043-4.00002-6

  40. Basson, A. R. et al. Anti-inflammatory properties of saturated fatty acids in biological systems. J. Lipid Res. 62(7), 1–12 (2021).

    Google Scholar 

  41. Pivetta, T. P. et al. Development of nanoparticles from natural lipids for topical delivery of thymol: Investigation of its anti-inflammatory properties. Colloids. Surf. B. Biointerfaces. 164, 281–290 (2018).

    Google Scholar 

Download references