A modified nanoparticle–mRNA complex for improved gene editing in the heart

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This is a summary of: Neiman, G. et al. A microphysiological system for screening lipid nanoparticle−mRNA complexes predicts in vivo heart transfection efficacy. Nat. Biomed. Eng. https://doi.org/10.1038/s41551-025-01523-4 (2025).