Category: Biotechnology Molecular & Computational biology
Cutting to the core of how 3D structure shapes gene activity
Many regions of the genome form topologically associating domains (TADs). Parts of the genome within these domains can interact more frequently with each other, while […]
Scientists develop novel recording tool to monitor protein kinase activities in living cells
In the simultaneous presence of the fluorescent HaloTag substrate (magenta) and a specific kinase activity, the molecular recorder Kinprola (green) becomes labeled and thus tracks […]
First-ever ribosomal synthesis of cyclic peptides opens new avenues for next-generation drug design
Schematic Illustration of the Introduction of Cyclic Peptides via Ribosome in a Cell-Free Protein Synthesis System. Credit: POSTECH Inside our cells, ribosomes—the tireless “protein factories” […]
AI-powered strategy streamlines protein engineering by integrating structural and evolutionary constraints
Advancing protein evolution with inverse folding models integrating structural and evolutionary constraints. Credit: IGDB A team of researchers has developed a method that could transform […]