Introduction Skeletal muscle is the largest tissue in the human body and is essential for physical exercise and metabolism1,2. It is broadly classified into two […]
Category: Combined
Combined single-cell profiling of chromatin–transcriptome and splicing across brain cell types, regions and disease state
Main Multimodal measurements, including the simultaneous measurements of gene expression, chromatin accessibility1,2,3 and antibody binding in single-cell4 and spatial genomics5,6 experiments, are of high importance […]
Combined downregulation of TGF-β1 and GRP78 is responsible for overcoming acquired sorafenib resistance, which is initiated by rewiring the cell surface CD44-GRP78-IGF-1R signaling circuit
Introduction Sorafenib, a multikinase inhibitor, has been the standard of care for advanced hepatocellular carcinoma (HCC) for more than a decade and is still considered […]