References Bornscheuer, U. & Kazlauskas, R. Hydrolases in Organic Synthesis, 2nd edn. Wiley-VCH (2006). Müller, H., Terholsen, H., Godehard, S. P., Badenhorst, C. P. S. […]
Category: Engineered
Engineered internal architecture of core-shell lipid nanoparticles promotes efficient mRNA endosomal release
Data availability The Figs. 2–8 and Supplementary Figs. 1–7 data generated in this study have been deposited in the Figureshare database under accession under https://doi.org/10.6084/m9.figshare.31072687. References Raimondo, […]
Engineered VPg saRNA achieves cap-independent, low-immunogenic and precise encoding of therapeutic proteins in vivo
Data availability Source data for Figs. 1–7 and Supplementary Figs. 1–7 are provided as Source Data files. LC–MS/MS raw datasets and Sanger sequencing chromatograms generated in this […]
Engineered mucus-tethering bispecific nanobodies enhance mucosal immunity against respiratory pathogens
Data availability Source data are provided with this paper. References Iuliano, A. D. et al. Estimates of global seasonal influenza-associated respiratory mortality: a modelling study. […]
An engineered UGA suppressor tRNA gene for disease-agnostic AAV delivery
Main Nonsense mutations are point mutations that convert a sense codon into a premature termination codon (PTC) in the mRNA, causing two deleterious events during […]
Engineered nanobodies facilitate cryo-EM studies of small proteins
Tools of the Trade Published: 07 January 2026 Gangshun Yi1 & Dimitrios Mamalis2,3 Nature Reviews Molecular Cell Biology (2026)Cite this article Subjects Single-particle cryo-electron microscopy […]
Engineered biodegradable polymeric nanoparticles injectable system of atorvastatin for improved therapeutic activity
References Libby, P. et al. Atherosclerosis. Nat. Rev. Dis. Primers. 5(1), 56 (2019). Vaduganathan, M., Mensah, G. A., Turco, J. V., Fuster, V. & Roth, […]
Engineered acoustic reporters for simultaneous tracking of two variables on ultrasonography
Research Briefing Published: 24 November 2025 Nature Methods (2025)Cite this article Subjects Engineered acoustic reporter genes with differential responses to the pressure of sound waves […]
Engineered Metarhizium fungi produce longifolene to attract and kill mosquitoes
Data availability All data that support the findings of this study are available in the article and Supplementary Information. The codon-optimized sequence of the pine […]
Engineered phage-silver nanoparticle complexes as a new tool for targeted therapies
Introduction The rise of antibiotic-resistant bacteria poses a significant threat to global health. It is estimated that in 2019, the number of deaths linked to […]