References Einhorn, T. A. & Gerstenfeld, L. C. Fracture healing: mechanisms and interventions. Nat. Rev. Rheumatol. 11, 45–54 (2015). Google Scholar Bahney, C. S. et […]
Category: Inhibition
Inhibition of TBK1/IKKε mediated RIPK1 phosphorylation sensitizes tumors to immune cell killing
Introduction The implementation of immune checkpoint blockade (ICB) therapy has significantly transformed cancer treatment by focusing clinical interventions on reactivating the body’s immune system to […]
Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models
Introduction Idiopathic pulmonary fibrosis (IPF) is a fatal, chronic lung disease with unknown ethiology1,2,3,4,5. IPF is characterized by excessive extracellular matrix (ECM) deposition in the […]