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Category: Novel
Novel fully human IgG1 targeting folate receptor α demonstrates antitumor efficacy driven by avidity rather than monovalent binding affinity
Data availability All data generated or analysed during this study are included in this published article and its supplementary information files. The Uncropped supplementary Figure […]
A novel chromatography method for high purity production of Recombinant human parathyroid hormone from E. coli
Abstract Human parathyroid hormone (hPTH) shows great potential as a therapeutic option for osteoporosis in patients who do not respond sufficiently to conventional therapies. We […]
A novel fibronectin-binding peptide reveals dynamic intermediate structures during matrix assembly
References Hynes, R. O. Fibronectins. 1 ednSpringer New York, NY, (1990). Schwarzbauer, J. E. & DeSimone, D. W. Fibronectins, their fibrillogenesis, and in vivo functions. […]
Novel enzymatic DNA produced from a text file achieves comparable immune responses as plasmid vaccine
Data availability The DNA sequence encoding HA and in silico optimized for enzymatic DNA synthesis was deposited to GenBank (accession number PV750927). An enzymatically-optimized HA […]
Novel anti-prion compounds screening in prion-infected cell culture model combined with surface plasmon resonance analysis
Data availability The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request. Abbreviations RT: Room Temperature FBS: […]
Novel heat exchanger in extracorporeal circuit: technical and biological feasibility
Introduction Techniques involving the extracorporeal (EC) circuit, such as continuous renal replacement techniques (CRRT) and extracorporeal membrane oxygenation (ECMO), have become essential in intensive care […]
A novel framework for TER allocation using multilayer perceptron and intuitionistic fuzzy Z numbers for talent management
Introduction TER allocation is critical in talent management, especially in dynamic working contexts where workforce demand and skills developed are dynamic and changing. Conventional allocation […]
A novel green biosynthesis approach and structural characterization of Ag–Fe bimetallic nanoparticles using the red alga Galaxaura rugosa
Article Open access Published: 24 August 2025 Elham M. Ali1,2, Ashraf Elsayed3 & Ahlam S. El Shehawy3 Scientific Reports volume 15, Article number: 31129 (2025) Cite this article […]
Novel anti-VEGF scFv antibodies with superior in vitro and in vivo activities
Introduction Vascular endothelial growth factor A (VEGF-A, also known as VEGF) dependent activation of VEGFR2 is the main driver of angiogenesis by stimulating proliferation and […]