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All data from this study are fully available within the article, Supplementary Information or Source Data file. Any additional requests for information can be directed to, and will be fulfilled by, the corresponding authors. Source data are provided with this paper.
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Acknowledgements
This study was supported by the National Natural Science Foundation of China (32401163 to W.L.), the Natural Science Foundation of Sichuan (2024NSFSC1689 to T.Z.), Post-Doctor Research Fund of West China Hospital, Sichuan University (2025HXBH149 to T.Z.), the Natural Science Foundation of Chongqing (CSTB2024NSCQ-MSX0107 to R.L., CSTB2023NSCQ-MSX0610 to Y.J.), Natural Science Foundation of Yuzhong District (20240121 to R.L.) and Chongqing Key Laboratory of Emergency Medicine (2024KFKTYX02 to R.L.).
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Zhang, T., Li, R., Wang, Z. et al. Inflammation-specific DNA origami nanodevice for delivery of siRNAs to treat ulcerative colitis. Nat Commun (2025). https://doi.org/10.1038/s41467-025-67183-9
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DOI: https://doi.org/10.1038/s41467-025-67183-9
