Metabolic reprogramming with ultrasound-responsive nanovesicles

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Metabolic reprogramming with ultrasound-responsive nanovesicles
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Nanomedicine

Nature Biomedical Engineering (2025)Cite this article

Subjects

Ultrasound-responsive lipid nanoparticles encapsulating thylakoid fragments sourced from plants and ascorbic acid restore mitochondrial function, treating acute kidney injury in mice and pigs.

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Fig. 1: Schematic illustration of acute kidney injury treatment using ultrasound-responsive nanovesicles.

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Author information

Authors and Affiliations

  1. Department of Radiology, University of Wisconsin-Madison, Madison, WI, USA

    Jessica C. Hsu & Weibo Cai

  2. Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, USA

    Jessica C. Hsu & Weibo Cai

  3. Department of Plastic and Reconstructive Surgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Jingwei Zhou

Authors

  1. Jessica C. Hsu
  2. Jingwei Zhou
  3. Weibo Cai

Corresponding author

Correspondence to Weibo Cai.

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Competing interests

W.C. declares competing interests with the following corporations: Portrai, Inc., rTR Technovaation Corporation and Four Health Global Pharmaceuticals, Inc. The other authors declare no competing interests.

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Hsu, J.C., Zhou, J. & Cai, W. Metabolic reprogramming with ultrasound-responsive nanovesicles. Nat. Biomed. Eng (2025). https://doi.org/10.1038/s41551-025-01460-2

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  • DOI: https://doi.org/10.1038/s41551-025-01460-2

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