References
-
Boutari, C. & Mantzoros, C. S. A. 2022 update on the epidemiology of obesity and a call to action: as its twin COVID-19 pandemic appears to be receding, the obesity and dysmetabolism pandemic continues to rage on. Metabolism 133, 155217 (2022).
-
Kupikowska-Stobba, B. et al. Controlled lipid digestion in the development of functional and personalized foods for a tailored delivery of dietary fats. Food Chem 466, 142151 (2025).
-
Shi, Q. et al. Paternal preconceptional supplementation of n-3 polyunsaturated fatty acids alleviates offspring nonalcoholic fatty liver disease in high-fat diet-induced obese mice. Food Front 5, 535–557 (2024).
-
Herrero, A. M. & Ruiz-Capillas, C. Novel lipid materials based on gelling procedures as fat analogues in the development of healthier meat products. Curr. Opin. Food Sci. 39, 1–6 (2021).
-
Liu, X. et al. Challenges, process technologies, and potential synthetic biology opportunities for plant-based meat production. LWT 184, 115109 (2023).
-
Sangsuriyawong, A. et al. Preparation of fat-free mulberry ice cream by using inulin and whey protein isolate as a fat substitute. eFood 5, e70006 (2024).
-
Ren, Y. et al. Effect of variation in basic emulsion structure and polysaccharide content on the physicochemical properties and structure of composite-based emulsion gels as cube fat mimetics. Food Chem 434, 137450 (2024).
-
Zhang, T. et al. Effects of konjac glucomannan on physical properties and microstructure of fish myofibrillar protein gel: Phase behaviours involved. Food Hydrocoll 134, 108034 (2023).
-
Cao, C. et al. Textural and gel properties of frankfurters as influenced by various κ-carrageenan incorporation methods. Meat Sci 176, 108483 (2021).
-
Zhao, D. et al. Salt ions improve soybean protein isolate/curdlan complex fat substitutes: effect of molecular interactions on freeze-thaw stability. Int. J. Biol. Macromol. 272, 132774 (2024).
-
Ren, Y. et al. Influence of variation in phase ratio and protein content on physicochemical properties and structure of soy protein isolate-konjac glucomannan double emulsion gels applicable as solid cubic fat substitutes. Food Chem 465, 142023 (2025).
-
Czapalay, E. S., Dobson, S. & Marangoni, A. G. Legume starch and flour-based emulsion gels as adipose tissue mimetics in plant-based meat products. Future Foods 11, 100578 (2025).
-
Ye, X. et al. Fabrication of food polysaccharide, protein, and polysaccharide-protein composite gels via calcium ion inducement: Gelation mechanisms, conditional factors, and applications. Int. J. Biol. Macromol. 279, 135397 (2024).
-
Lin, S. et al. Effects of ultrasound combined with κ-carrageenan on the rheological behaviours, textural properties and microstructures of meat batters before and after heating treatment. Food Hydrocoll 164, 111234 (2025).
-
Xu, Q. et al. Functionality and application of emulsion gels in fat replacement strategies for dairy products. Trends Food Sci. Technol 152, 104673 (2024).
-
Yan, J. et al. Effect of calcium ions concentration on the properties and microstructures of doubly induced sorghum arabinoxylan/soy protein isolate mixed gels. Food Hydrocoll 133, 107997 (2022).
-
Huang, X. et al. Research progress on double-network hydrogels. Mater. Today Commun. 29, 102757 (2021).
-
Yiu, C. C. Y., Wang, Y. & Selomulya, C. Double network as a design paradigm for structuring emulsion gels in food. Comprehens. Rev. Food Sci. Food Saf. 24, e70201 (2025).
-
Yan, W. et al. Corn fiber gum-soybean protein isolate double network hydrogel as oral delivery vehicles for thermosensitive bioactive compounds. Food Hydrocoll 107, 105865 (2020).
-
Wang, Y. et al. A combined enzymatic and ionic cross-linking strategy for pea protein/sodium alginate double-network hydrogel with excellent mechanical properties and freeze-thaw stability. Food Hydrocoll 131, 107737 (2022).
-
Li, A., Gong, T., Hou, Y., Yang, X. & Guo, Y. Alginate-stabilized thixotropic emulsion gels and their applications in fabrication of low-fat mayonnaise alternatives. Int. J. Biol. Macromol. 146, 821–831 (2020).
-
Wang, S. et al. Soybean protein isolate-sodium alginate double network emulsion gels: Mechanism of formation and improved freeze-thaw stability. Int. J. Biol. Macromol. 274, 133296 (2024).
-
Williams, A. H. et al. Printable homocomposite hydrogels with synergistically reinforced molecular-colloidal networks. Nat. Commun. 12 (2021).
-
Zhang, R., Liu, J., Cao, S., Yan, Z. & Liu, X. Tailoring an egg white protein double network emulsion gel as a novel fat substitute for improving freeze-thaw stability of minced meat gel. Food Hydrocoll 150, 109763 (2024).
-
Ye, X. et al. Soy protein isolate-sodium alginate emulsion gel co-construction of a dual network system for the development of three-dimensional simulated fats: effect of sodium alginate concentration and calcium ion addition. Food Chem 487, 144652 (2025).
-
Zhuang, X. et al. The effect of insoluble dietary fiber on myofibrillar protein emulsion gels: oil particle size and protein network microstructure. LWT 101, 534–542 (2019).
-
Zhu, Y., Chen, X., McClements, D. J., Zou, L. & Liu, W. pH-, ion- and temperature-dependent emulsion gels: Fabricated by addition of whey protein to gliadin-nanoparticle coated lipid droplets. Food Hydrocoll 77, 870–878 (2018).
-
Su, C. et al. Effect of sodium alginate on the stability of natural soybean oil body emulsions. RSC Adv 8, 4731–4741 (2018).
-
Cheng, H., Garcia, A. C., Tang, N., Danielsen, B. P. & Skibsted, L. H. Combinations of isocitrate and citrate enhance calcium salt solubility and supersaturation robustness. Int. Dairy J. 85, 225–236 (2018).
-
Yu, B., Miao, S., Ding, M. & Ren, Y. Solubility and physical properties of α-calcium sulfate hemihydrate in NaCl and glycerol aqueous solutions at 303.15, 323.15, and 343.15 kJ. Chem. Eng. Data 66, 3686–3694 (2021).
-
Zhao, H. et al. The self-regulating on cohesion properties of calcium phosphate/ calcium sulfate bone cement improved by citric acid/sodium alginate. Colloids Surf. B Biointerfaces 231, 113548 (2023).
-
Taherdangkoo, R. et al. Experimental data on solubility of the two calcium sulfates gypsum and anhydrite in aqueous solutions. Data 7, 140 (2022).
-
Ben Djemaa, I. et al. Glucono-delta-lactone-induced alginate gelation: new insights into the effect of the cross-linker carrier type on the hydrogel mechanics. Langmuir 40, 10492–10501 (2024).
-
Posavec, L. et al. Dissolution and storage stability of nanostructured calcium carbonates and phosphates for nutrition. J. Nanopart. Res. 18, 310 (2016).
-
Lee, P. & Rogers, M. A. Effect of calcium source and exposure-time on basic caviar spherification using sodium alginate. Int. J. Gastron. Food Sci. 1, 96–100 (2012).
-
Li, A. et al. Gelation mechanism and physical properties of glucono-δ-lactone induced alginate sodium/casein composite gels. Food Hydrocoll 118, 106775 (2021).
-
Bao, H., Ni, Y., Wusigale, Dong, H. & Liang, L. α-Tocopherol and resveratrol in emulsion-filled whey protein gels: Co-encapsulation and in vitro digestion. Int. Dairy J. 104, 104649 (2020).
-
Wang, Y.-S. et al. Double cross-linked emulsion gels stabilized by flaxseed protein and chitosan: Effects of CaCO3 content on gel properties, stability and curcumin digestive characteristics. Food Chem 477, 143503 (2025).
-
Zhang, K. et al. Effects of calcium chloride on the gelling and digestive characteristics of myofibrillar protein in Litopenaeus vannamei. Food Chem 441, 138348 (2024).
-
Murekatete, N., Hua, Y., Chamba, M. V. M., Djakpo, O. & Zhang, C. Gelation behavior and rheological properties of salt- or acid-induced soy proteins soft Tofu-type gels. J. Texture Stud. 45, 62–73 (2014).
-
Luo, Y. et al. Physicochemical properties and in vitro digestion behavior of emulsion gels stabilized by rice bran protein aggregates: effects of heating time and induction methods. Food Res. Int. 170, 112976 (2023).
-
Yan, J., Jia, X., Yan, W. & Yin, L. Double-network hydrogels of corn fiber gum and soy protein isolate: effect of biopolymer constituents and pH values on textural properties and microstructures. Foods 10, 356 (2021).
-
Yang, X., Ren, Y., Liu, H., Huo, C. & Li, L. Differences in the physicochemical, digestion and microstructural characteristics of soy protein gel acidified with lactic acid bacteria, glucono-δ-lactone and organic acid. Int. J. Biol. Macromol. 185, 462–470 (2021).
-
Zhang, R. et al. Double network emulsion gel prepared with different polyphenol modified egg white protein: A promising fat substitute for oral processing and fatty taste supplement. Food Chem 465, 142082 (2025).
-
Xia, Q., Gu, M., Liu, J., Niu, Y. & Yu, L. Novel composite gels of gelatin and soluble dietary fiber from black bean coats with interpenetrating polymer networks. Food Hydrocoll 83, 72–78 (2018).
-
Hashemi, S. J., Hormozi, F. & Mokhtari, R. Controlling the gelation time of sodium silicate gelants for fluid management in hydrocarbon reservoirs. Fuel 341, 127645 (2023).
-
Ashkar, A., Laufer, S., Rosen-Kligvasser, J., Lesmes, U. & Davidovich-Pinhas, M. Impact of different oil gelators and oleogelation mechanisms on digestive lipolysis of canola oil oleogels. Food Hydrocoll 97, 105218 (2019).
-
Han, L. et al. Effects of inducer type and concentration on the formation mechanism of W/O/W double emulsion gels. Food Chem 379, 132166 (2022).
-
Zhang, M., Yang, Y. & Acevedo, N. C. Effects of pre-heating soybean protein isolate and transglutaminase treatments on the properties of egg-soybean protein isolate composite gels. Food Chem 318, 126421 (2020).
-
Xu, Y., He, C. & Zhou, Z. Modulating the texture of heat-set gels of phosphorylated walnut protein isolates through Glucono-δ-lactone acidification. Food Chem 437, 137734 (2024).
-
Liu, W. et al. Effects of different hydrocolloids on gelatinization and gels structure of chestnut starch. Food Hydrocoll 120, 106925 (2021).
-
Shen, P., Ma, X., Gouzy, R., Landman, J. & Sagis, L. M. C. Gelation properties of three common pulse proteins: lentil, faba bean and chickpea. Food Hydrocoll 164, 111245 (2025).
-
Guan, H. et al. Effect of sodium alginate on freeze-thaw stability of deacetylated konjac glucomannan gel. J. Food Eng. 383, 112239 (2024).
-
Pi, X. et al. Insight of soy protein isolate to decrease the gel properties corn starch based binary system: Rheological and structural investigation. Food Hydrocoll 160, 110750 (2025).
-
Ren, S. et al. Potentially texture-modified food for dysphagia: Gelling, rheological, and water fixation properties of rice starch–soybean protein composite gels in various ratios. Food Hydrocoll 153, 110025 (2024).
-
Sandjian, M. E. & Martínez, K. D. Emulsions, foams, and gels structure design formulated with soy protein isolate and calcium for vegan consumers. Food Human 4, 100490 (2025).
-
Wang, X. et al. Effects of the size and content of protein aggregates on the rheological and structural properties of soy protein isolate emulsion gels induced by CaSO4. Food Chem 221, 130–138 (2017).
-
Qiu, G. et al. Litchi polyphenols and carboxylated cellulose nanofiber synergistically improve the gel properties of κ-carrageenan gels: Insight from rheology, morphology and interaction computational simulation. Food Hydrocoll 166, 111292 (2025).
-
Brito-Oliveira, T. C., Moraes, I. C. F., Pinho, S. C. & Campanella, O. H. Modeling creep/recovery behavior of cold-set gels using different approaches. Food Hydrocoll 123, 107183 (2022).
-
Li, X. et al. Fat substitute in salad dressing: The role of soybean oil body self-aggregates in enhancing texture and rheological property. Food Res. Int. 204, 115909 (2025).
-
Parmar, S., Kumar, Y. & Kumar, P. Ultrasound pretreatment-enhanced OSA esterification of proso millet starch for application in low-fat mayonnaise. Food Chem 494, 146174 (2025).
-
Ali, A. H. et al. Fermented camel milk influenced by soy extract: Apparent viscosity, viscoelastic properties, thixotropic behavior, and biological activities. J. Dairy Sci. 106, 6671–6687 (2023).
-
Chen, H. et al. The linear/nonlinear rheological behaviors of Pickering emulsion stabilized by Zein and Xanthan gum: Effect of interfacial assembly strategies. Food Hydrocoll 145, 109116 (2023).
-
Karimi, S., Ghanbarzadeh, B., Roufegarinejad, L. & Falcone, P. M. Physicochemical and rheological characterization of a novel hydrocolloid extracted from Althaea officinalis root. LWT 167, 113832 (2022).
-
Lin, D., Kelly, A. L. & Miao, S. The role of mixing sequence in structuring O/W emulsions and emulsion gels produced by electrostatic protein-polysaccharide interactions between soy protein isolate-coated droplets and alginate molecules. Food Hydrocoll 113, 106537 (2021).
-
Zhu, Q. et al. Encapsulation of lycopene in Pickering emulsion stabilized by complexes of whey protein isolate fibrils and sodium alginate: Physicochemical property, structural characterization and in vitro digestion property. Food Res. Int. 191, 114675 (2024).
-
Paques, J. P., Sagis, L. M. C., van Rijn, C. J. M. & van der Linden, E. Nanospheres of alginate prepared through w/o emulsification and internal gelation with nanoparticles of CaCO3. Food Hydrocoll 40, 182–188 (2014).
-
Lan, T. et al. Optimizing texture and mechanical properties: the impact of pH-modulated metal-phenolic networks on soy protein isolate gels. Food Hydrocoll 153, 110011 (2024).
-
Yang, S. et al. Insight into succinylated modified soy protein isolate-sodium alginate emulsion gels: Structural properties, interactions and quercetin release behavior. Food Hydrocoll 151, 109857 (2024).
-
Chen, Z. et al. Effect of freezing on physicochemical properties and microstructure of soy protein gels. LWT 208, 116661 (2024).
-
Ban, Q. et al. Effect of non-covalently bound alkaline amino acids on the structural characterization, microstructure, and rheological properties of whey protein emulsion gel. LWT 209, 116809 (2024).
-
Lu, F., Chi, Y. & Chi, Y. Effect of fat replacement in high internal phase emulsions constructed by high temperature saccharification of grafted proteins on gel properties and flavor profiles of sausages. Poult. Sci. 103, 104358 (2024).
-
Feng, J. et al. Interpenetrating network hydrogels loaded with nanostructured lipid carriers for curcumin delivery: Impact of dual crosslinking with genipin and calcium ions. Food Res. Int. 202, 115704 (2025).
-
Liu, L. et al. The effect of corn starch on the mechanism and printing characteristics of Sa-son seed gum-whey protein. Food Biosci 67, 106323 (2025).
-
Wang, J. et al. Rheological and mechanical behavior of soy protein-polysaccharide composite paste for extrusion-based 3D food printing: Effects of type and concentration of polysaccharides. Food Hydrocoll 153, 109942 (2024).
-
Lin, X., Shi, J., Meng, G. & Yu, C. Sodium alginate hydrogel carrier with calcium carbonate as calcium source for ibuprofen release. Macromol. Chem. Phys. 224, 2300195 (2023).
-
Sofiah Roslan, H. et al. Characteristics of hybrid alginate/soy protein isolate wound dressing aerogels dried by supercritical carbon dioxide. Mater. Today Proc. 407 (2023).
-
Hu, X. & Meng, Z. Plant-based yolk alternatives based on alginate-chitosan and gellan gum-chitosan double hydrogel network using reverse spherification technology. Food Chem 476, 143409 (2025).
-
Zhong, M. et al. The effect of salt ion on the freeze-thaw stability and digestibility of the lipophilic protein-hydroxypropyl methylcellulose emulsion. LWT 151, 112202 (2021).
-
Xing, H., Liu, X., Hu, Y., Hu, K. & Chen, J. Effect of Lycium barbarum polysaccharides on heat-induced gelation of soy protein isolate. Food Hydrocoll 147, 109323 (2024).
-
Sun, A. et al. Pickering emulsion gel based on WPI/SPI composite protein-sodium alginate: encapsulation of nervonic acid and its application in processed cheese. Food Biosci 67, 106341 (2025).
-
Li, M. et al. Exploring the gelation potentials of chicken heart batter: from by-product to product. Food Chem 468, 142316 (2025).
-
Tong, J. et al. Influence mechanisms of different setting time at low temperature on the gel quality and protein structure of Solenocera crassicornis surimi. Food Biosci 51, 102344 (2023).
-
Zhang, H. et al. Investigation of the formation mechanism and β-carotene encapsulation stability of emulsion gels based on egg yolk granules and sodium alginate. Food Chem 400, 134032 (2023).
-
Yao, W. et al. Underlying the effect of soybean oil concentration on the gelling properties of myofibrillar protein-based emulsion gels: perspective on interfacial adsorption, rheological properties and protein conformation. Food Hydrocoll 162, 110935 (2025).
-
Wang, H., Sun, L., Sun, X., Tian, H. & Yu, D. Effects of moderate electric fields on the structural and gelling properties of soybean protein isolate gel induced by glucono-δ-lactone. Innov. Food Sci. Emerg. Technol. 95, 103716 (2024).
-
Cao, J. et al. Soy protein isolate/sodium alginate microparticles under different pH conditions: formation mechanism and physicochemical properties. Foods 11, 790 (2022).
-
Su, C., Li, D., Wang, L. & Wang, Y. Development of corn starch-sodium alginate emulsion gels as animal fat substitute: Effect of oil concentration. Food Hydrocoll 157, 110439 (2024).
-
Su, C., Li, D., Sun, W., Wang, L. & Wang, Y. Green, tough, and heat-resistant: a GDL-induced strategy for starch-alginate hydrogels. Food Chem 449, 139188 (2024).
-
Xia, W. et al. Acid-induced gels from soy and whey protein thermally-induced mixed aggregates: rheology and microstructure. Food Hydrocoll 125, 107376 (2022).
-
Cao, L., Lu, W., Mata, A., Nishinari, K. & Fang, Y. Egg-box model-based gelation of alginate and pectin: a review. Carbohydr. Polym. 242, 116389 (2020).
-
Wang, Y. et al. Fabrication of a double-network high internal phase emulsion gel stabilized by bacterial cellulose nanofibrils: Enhancement of heat stability and 3D printing. Food Hydrocoll 143, 108872 (2023).
-
Shuai, X. et al. Macadamia oil-based oleogels as cocoa butter alternatives: physical properties, oxidative stability, lipolysis, and application. Food Res. Int. 172, 113098 (2023).
-
Jackman, P., Sun, D.-W. & Allen, P. Automatic segmentation of beef longissimus dorsi muscle and marbling by an adaptable algorithm. Meat Sci 83, 187–194 (2009).
-
Uttaro, B., Zawadski, S., Larsen, I. & Juárez, M. An image analysis approach to identification and measurement of marbling in the intact pork loin. Meat Sci 179, 108549 (2021).
-
Liu, S. et al. Investigation into the fabrication of plant-based simulant connective tissue utilizing algae polysaccharide-derived hydrogel. Int. J. Biol. Macromol. 273, 133126 (2024).
-
Ullah, I. et al. Influence of okara dietary fiber with varying particle sizes on gelling properties, water state and microstructure of tofu gel. Food Hydrocoll 89, 512–522 (2019).
-
Ran, J. et al. Gel properties of mung bean protein-sodium caseinate hybrid yogurt: physicochemical properties, microstructure, and intermolecular interactions. Food Chem. X 24, 101977 (2024).
-
Feng, Y. et al. Effects of transglutaminase coupled with κ-carrageenan on the rheological behaviours, gel properties and microstructures of meat batters. Food Hydrocoll 146, 109265 (2024).
-
Basak, S. & Singhal, R. S. Composite hydrogels fabricated from konjac glucomannan and gellan gum: Rheological characterization and their potential application in sustainable agriculture. Carbohydr. Polym. 336, 122091 (2024).
-
Lan, Y.-C. & Lai, L.-S. Pasting and rheological properties of water caltrop starch as affected by the addition of konjac glucomannan, guar gum and xanthan gum. Food Hydrocoll 136, 108245 (2023).
-
Huang, L. et al. Transglutaminase treatment and pH shifting to manipulate physicochemical properties and formation mechanism of cubic fat substitutes. Food Chem. X 16, 100508 (2022).
-
Lin, T., Liu, S., Ji, Z., Shao, H. & Hao, J. Vitrified bond diamond grinding wheel prepared by gel-casting with 3D printing molds. Diam. Relat. Mater. 108, 107917 (2020).
-
Park, J. W., Lee, S. H., Kim, H. W. & Park, H. J. Application of extrusion-based 3D food printing to regulate marbling patterns of restructured beef steak. Meat Sci 202, 109203 (2023).
