Osteopontin de-escalates the foreign body response

osteopontin-de-escalates-the-foreign-body-response
Osteopontin de-escalates the foreign body response

Osteopontin is necessary and sufficient to reduce fibrosis around silicone implants coated with an acellular dermal matrix.

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Authors and Affiliations

  1. Allergan Aesthetics, an AbbVie company, Irvine, CA, USA

    Sergei Butenko

  2. Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA

    Maksim V. Plikus

  3. Sue and Bill Gross Stem Cell Research Center, University of California, Irvine, Irvine, CA, USA

    Maksim V. Plikus

  4. Center for Complex Biological Systems, University of California, Irvine, Irvine, CA, USA

    Maksim V. Plikus

Authors

  1. Sergei Butenko
  2. Maksim V. Plikus

Corresponding author

Correspondence to Maksim V. Plikus.

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Competing interests

S.B. is an employee of Allergan Aesthetics, an AbbVie Company. M.V.P. declares no competing interests.

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Butenko, S., Plikus, M.V. Osteopontin de-escalates the foreign body response. Nat. Biomed. Eng (2025). https://doi.org/10.1038/s41551-025-01472-y

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  • DOI: https://doi.org/10.1038/s41551-025-01472-y