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Placental organoids offer powerful tools to advance diagnostics and therapies for pregnancy complications including preeclampsia and fetal growth restriction. However, most current models rely on animal-derived materials and heterogenous cell sources. Developing human-based physiologically relevant organoid models is essential to understand disease phenotypes and improve clinical care for high-risk pregnancies.
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Richards, C., Heidari, F. & McClements, L. Placental organoids for drug and biomarker discovery. Nat Rev Bioeng (2026). https://doi.org/10.1038/s44222-026-00409-7
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DOI: https://doi.org/10.1038/s44222-026-00409-7
