Placental organoids for drug and biomarker discovery

placental-organoids-for-drug-and-biomarker-discovery
Placental organoids for drug and biomarker discovery

Placental organoids offer powerful tools to advance diagnostics and therapies for pregnancy complications including preeclampsia and fetal growth restriction. However, most current models rely on animal-derived materials and heterogenous cell sources. Developing human-based physiologically relevant organoid models is essential to understand disease phenotypes and improve clinical care for high-risk pregnancies.

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Fig. 1: Placental organoids for pregnancy research, biomarker discovery and drug screening.

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Authors and Affiliations

  1. School of Life Sciences & Institute for Biomedical Materials and Devices, Faculty of Science, University of Technology Sydney, Sydney, New South Wales, Australia

    Claire Richards, Fatemeh Heidari & Lana McClements

  2. INSIGHT Research Institute for Innovative Solutions for Wellbeing and Health, University of Technology Sydney, Sydney, New South Wales, Australia

    Claire Richards & Lana McClements

Authors

  1. Claire Richards
  2. Fatemeh Heidari
  3. Lana McClements

Corresponding author

Correspondence to Lana McClements.

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Competing interests

The authors declare no competing interests.

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Richards, C., Heidari, F. & McClements, L. Placental organoids for drug and biomarker discovery. Nat Rev Bioeng (2026). https://doi.org/10.1038/s44222-026-00409-7

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  • DOI: https://doi.org/10.1038/s44222-026-00409-7