References
-
Cope, G. F. & Cope, A. Gingivitis: Symptoms, causes and treatment. Dent. Nurs. 7, 436–439 (2011).
-
Guha Biswas, P., Mohan, A. & Kandaswamy, E. Treatment of periodontitis affecting human primary teeth—A systematic review. Dent. J. (Basel) 11, 17 (2023).
-
González-Moles, M. A. & González, N. M. Bacterial infections of pulp and periodontal origin. Med. Oral. Patol. Oral. Cir. Bucal. 9, 32–34 (2004).
-
Siqueira, J. F. Jr. & Rôças, I. N. Microbiology and treatment of acute apical abscesses. Clin. Microbiol. Rev. 26, 255–273 (2013).
-
Cope, A. L., Francis, N., Wood, F. & Chestnutt, I. G. Systemic antibiotics for symptomatic apical periodontitis and acute apical abscess in adults. Cochr. Datab Syst. Rev. 9, CD010136 (2018).
-
Hasturk, H., Kantarci, A. & Van Dyke, T. E. Oral inflammatory diseases and systemic inflammation: Role of the macrophage. Front. Immunol. 3, 118 (2012).
-
Kurtzman, G. M., Horowitz, R. A., Johnson, R., Prestiano, R. A. & Klein, B. I. The systemic oral health connection: Biofilms. Medicine (Baltimore) 101, e30517 (2022).
-
Kapoor, A., Malhotra, R., Grover, V. & Grover, D. Systemic antibiotic therapy in periodontics. Dent. Res. J. (Isfahan) 9, 505–515 (2012).
-
Nguyen, S. & Hiorth, M. Advanced drug delivery systems for local treatment of the oral cavity. Ther. Deliv. 6, 595–608 (2015).
-
Zhang, Y., Jiang, R., Lei, L., Yang, Y. & Hu, T. Drug delivery systems for oral disease applications. J. Appl. Oral. Sci. 30, e20210349 (2022).
-
Buranasin, P. et al. Influence of reactive oxygen species on wound healing and tissue regeneration in periodontal and peri-implant tissues in diabetic patients. Antioxidants (Basel) 12, 1787 (2023).
-
Jordan, A. R., Racine, R. R., Hennig, M. J. & Lokeshwar, V. B. The role of CD44 in disease pathophysiology and targeted treatment. Front. Immunol. 6, 182 (2015).
-
Lucarini, G., Zizzi, A., Rubini, C., Ciolino, F. & Aspriello, S. D. VEGF, microvessel density, and CD44 as inflammation markers in peri-implant healthy mucosa, peri-implant mucositis, and peri-implantitis: Impact of age, smoking, PPD, and obesity. Inflammation 42, 682–689 (2019).
-
Mijiritsky, E. et al. Presence of ROS in inflammatory environment of peri-implantitis tissue: In vitro and in vivo human evidence. J. Clin. Med. 9, 38 (2019).
-
Shang, J., Liu, H., Zheng, Y. & Zhang, Z. Role of oxidative stress in the relationship between periodontitis and systemic diseases. Front. Physiol. 14, 1210449 (2023).
-
Pu, H. L. et al. Nanoparticles with dual responses to oxidative stress and reduced pH for drug release and anti-inflammatory applications. ACS Nano 8, 1213–1221 (2014).
-
Pua, M. L., Yoshitomi, T., Chonpathompikunlert, P., Hirayama, A. & Nagasaki, Y. Redox-active injectable gel using thermo-responsive nanoscale polyion complex flower micelle for noninvasive treatment of local inflammation. J. Control. Release. 172, 914–920 (2013).
-
Xiao, L. et al. Microenvironment-regulating drug delivery nanoparticles for treating and preventing typical biofilm-induced oral diseases. Adv. Mater. 2023, e2304982 (2023).
-
Salathia, S., Gigliobianco, M. R., Casadidio, C., Di Martino, P. & Censi, R. Hyaluronic acid-based nanosystems for CD44 mediated anti-inflammatory and antinociceptive activity. Int. J. Mol. Sci. 24, 7286 (2023).
-
Wang, P. et al. Hyaluronic acid-based M1 macrophage targeting and environmental responsive drug releasing nanoparticle for enhanced treatment of rheumatoid arthritis. Carbohydr. Polym. 316, 121018 (2023).
-
Park, H. K. et al. Smart nanoparticles based on hyaluronic acid for redox-responsive and CD44 receptor-mediated targeting of tumor. Nanoscale Res. Lett. 10, 981 (2015).
-
Pfaller, M. A. et al. Evaluation of the NCCLS M44-P disk diffusion method for determining susceptibilities of 276 clinical isolates of Cryptococcus neoformans to fluconazole. J. Clin. Microbial. 42, 380–383 (2004).
-
Li, X., Kolltveit, K. M., Tronstad, L. & Olsen, I. Systemic diseases caused by oral infection. Clin. Microbiol. Rev. 13, 547–558 (2000).
-
Abdullah, F. M. et al. Antimicrobial management of dental infections: Updated review. Medicine (Baltimore) 103, e38630 (2024).
-
Emanuel, N., Machtei, E. E., Reichart, M. & Shapira, L. D-PLEX500: A local biodegradable prolonged release doxycycline-formulated bone graft for the treatment for peri-implantitis. A randomized controlled clinical study. Quintessence Int. 51, 546–553 (2020).
-
Shahi, S. et al. A review on potential toxicity of dental material and screening their biocompatibility. Toxicol. Mech. Methods. 29, 368–377 (2019).
-
Ahmad, R. et al. Elevated expression of the toll like receptors 2 and 4 in obese individuals: Its significance for obesity-induced inflammation. J. Inflamm. 9, 48 (2012).
-
Baliga, S., Muglikar, S. & Kale, R. Salivary pH: A diagnostic biomarker. J. Indian Soc. Periodontol. 17, 461–465 (2013).
-
Chen, L. et al. Inflammatory responses and inflammation-associated diseases in organs. Oncotarget 9, 7204–7218 (2018).
-
Ranjith Raj, V. P. R. B. & Thamaraiselvan, M. Role of salivary pH on the prevalence of periodontal disease: A cross sectional pilot study. J. Res. Med. Dent. Sci. 8, 423–427 (2020).
-
Tetyczka, C. et al. Cytokine-mediated inflammation in the oral cavity and its effect on lipid nanocarriers. Nanomaterials (Basel) 11, 1330 (2021).
-
Kosovrasti, V. Y., Nechev, L. V. & Amiji, M. M. Peritoneal macrophage-specific TNF-α gene silencing in LPS-induced acute inflammation model using CD44 targeting hyaluronic acid nanoparticles. Mol. Pharm. 13, 3404–3416 (2016).
-
Desta, T., Li, J., Chino, T. & Graves, D. T. Altered fibroblast proliferation and apoptosis in diabetic gingival wounds. J. Dent. Res. 89, 609–614 (2010).
