Tumor-on-chip models of CAR-T cell therapy

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Tumor-on-chip models of CAR-T cell therapy
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Nature Biotechnology (2025)Cite this article

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Two seminal studies report a bioengineering approach to modeling CAR-T cell therapy of solid human tumors.

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Fig. 1: Two tumor-on-chip approaches to modeling CAR-T cell therapy of solid tumors.

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Authors and Affiliations

  1. Laboratory for Stem Cells and Tissue Engineering, Department of Biomedical Engineering, Department of Medicine, Columbia University, New York, NY, USA

    Gordana Vunjak-Novakovic

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  1. Gordana Vunjak-Novakovic

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Correspondence to Gordana Vunjak-Novakovic.

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The author declares no competing interests.

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Vunjak-Novakovic, G. Tumor-on-chip models of CAR-T cell therapy. Nat Biotechnol (2025). https://doi.org/10.1038/s41587-025-02819-1

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